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Myopathy, defined as muscle pain or muscle weakness in conjunction with lipitor increases in creatine kinase (CK) values to greater than ten times the upper limit of normal, should be considered in any patient with diffuse myalgia, muscle tenderness or weakness, and/or marked elevation of LIPITOR® (atorvastatin calcium) Product Monograph CK .
Patients should be advised to report promptly any unexplained muscle lipitor pain, tenderness or weakness, particularly if accompanied by malaise or fever .
Patients who develop any signs or symptoms suggestive of myopathy should have their CK lipitor levels measured .
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